Nidanib, CAS number 656247-17-5, is a small molecule multi-target receptor tyrosine kinase inhibitor. It is a yellow to green solid powder classified as an anti fibrotic drug in pharmacology. Its core characteristic is the ability to simultaneously inhibit multiple key kinase targets associated with pathological processes, thereby intervening in fibrosis progression and tumor angiogenesis. This product has been approved by drug regulatory agencies in multiple countries worldwide for the treatment of specific diseases.
The main function of Nidanib is to inhibit three key receptors: platelet-derived receptor (PDGFR), fibroblast receptor (FGFR), and vascular endothelial receptor (VEGFR). These factors are overactivated in pulmonary fibrosis and tumor growth. By blocking these signaling pathways, Nidanib can effectively slow down the proliferation, migration, and transformation of fibroblasts, thereby inhibiting the progression of abnormal scarring (fibrosis) in lung tissue. In addition, it can also inhibit the generation of tumor blood vessels and cut off the nutritional supply to tumor cells.
?
Frequently Asked Questions
What is the purity level of your Nintedanib powder?
Our Nintedanib powder features a high purity level of over 99%, as verified by HPLC testing methods.
What are the primary therapeutic applications of Nintedanib?
It is primarily used as an anti-fibrotic and anti-cancer agent, effectively treating conditions like pulmonary fibrosis by inhibiting key kinase targets.
Which key receptors does Nintedanib inhibit?
Nintedanib inhibits three essential receptors: Platelet-Derived Growth Factor Receptor (PDGFR), Fibroblast Growth Factor Receptor (FGFR), and Vascular Endothelial Growth Factor Receptor (VEGFR).
What certifications does this product hold?
The product is manufactured under strict quality standards and holds GMP, HSE, ISO 9001, USP, and BP certifications.
What is the physical state and appearance of the product?
Nintedanib is supplied as a white to off-white or yellow-green solid powder.
What is the monthly production capacity for Nintedanib?
Our production facility has a capacity of 1000kg per month to ensure stable supply.
SJ medical
